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Iodine Investigation by Dr. Sebastian Venturi

Investigator on Iodine Deficiency Disorders and Iodine Metabolism
Già Medico del Servizio di Igiene, Regione Marche Member of the Italian Thyroid Association (AIT)
E-mail :
dr.venturi.sebastiano@gmail.com
C.V.
Updated: April 3 , 2014
SELECTED PUBLICATIONS http://scholar.google.com/citations

Cell Biochemistry & Physiology
1969
Sebastiano Venturi
Figure A: entire cell          Figure B: superior part of the cell          Figure C: inferior part of the cell

Studio delle tireopatie nell'Alta Valmarecchia e loro profilassi
Booklet, Ed. Botticelli, Novafeltria
1978
Sebastiano Venturi
LINK

Preliminari ad uno studio sui rapporti tra cancro gastrico e carenza alimentare iodica: Prospettive specifiche di prevenzione
(Preliminary study on the relation between alimentary iodine deficiency and gastric cancer: specific prevention prospects) - Book
1985
Sebastiano Venturi
LINK
LINK
Syndrome thyro-gastric. Study on the relation between
alimentary iodine deficiency and gastric cancer
Venturi S, Marani L, Magni MA
In: Ghironzi G, Jackson CE, Schuman BM, Editors. Epidemiology Prevention and Early Detection of Gastric Cancer. Editor CIC Intern. Rome, . (Chapter of book)
1987 [Audiological and neuropsychological development study in a sample of school children from a low-iodine area of the Central Apennines that is endemic for cretinism]
1989
[Article in Italian]
Donati L, Venturi S, Andreani M, Antonelli A, Gori E, Bertoni F, Pruneti CA, Berrettini S, Bruschini P, Baschieri L.
LINK

Role of iodine in delayed immune response.
1985
Marani L, Venturi S, Masala R.
LINK
[Iodine and delayed immunity]
1986
[Article in Italian]
Marani L, Venturi S.
LINK
An iodine-deficient area with endemic cretinism in the Central Appennines:
studies of neuropsychological development in schoolchildren. Donati L, Venturi S, Andreani M, et al.
Journal of Endocrinological Investigation,
1988, 4 :11-12.
Cancro dello stomaco e carenza di iodio nella dieta.
1989
Responsible Nutrition Report, Vol. 4 . Oct. 1989
Venturi S La carenza di iodio nel Montefeltro: Ricerche ed ipotesi di patologie correlate
1990
Bollettino Epidemiologico Marche. Marzo 1990, anno 3, n. 3 : pp. 29-47 (Chapter of book)
Venturi S
Persistenza di aree di gozzo-cretinismo endemico in Italia: il caso del Montefeltro.
1991
Giornale di Clinica Medica, Vol. LXXII, Nov. 1991, pp. 463-472
Donati L., Antonelli A., Andreani M., Venturi S., Pruneti C.A., Berrettini S., Baschieri L.
LINK Clinical picture of endemic cretinism in central Apennines (Montefeltro).
1992
Donati L, Antonelli A, Bertoni F, Moscogiuri D, Andreani M, Venturi S, Filippi T, Gasperini L, Neri S, Baschieri L.
LINK
LINK

Patologie extra-tiroidee da carenza iodica.
Venturi S, Venturi M.
Urbino, 1992

Goitrous cretins in valleys of Apennines in the Emilia-Romagna and Tuscany regions
between prof. A. Pinchera of Pisa University and prof. J.T. Dunn of Virginia University.
(Photographs by Venturi, 1994)
A new hypothesis: iodine and gastric cancer
1993
S. Venturi, A. Venturi, D. Cimini, C. Arduini, M. Venturi, A. Guidi
LINK
Dietary Iodine and Gastric cancer
1994-96
S. Venturi - Coll.: M. Venturi, A. Guidi, F.M. Donati
LINK
Humoral thyroid autoimmunity is not involved in the pathogenesis of myxedematous endemic cretinism.
1995
Chiovato L, Vitti P, Bendinelli G, Santini F, Fiore E, Tonacchera M, Mammoli C, Capaccioli A, Venturi S, Pretell E, Pinchera A.
LINK
I disordini extra-tiroidei da carenza iodica. Qual e' il reale fabbisogno di iodio
1996
(Extrathyroid Iodine Deficiency Disorders. What is the real iodine requirement?)
Venturi S, Guidi A, Venturi S
LINK “The enigma of the function of thyroxine in animal extrathyroidal organs and in primitive stomach"
The Thyroid Gland, Clinical and Experimental. 1998; 1, 23
1998
Sebastiano Venturi
Ruolo dello ioduro nella cancerogenesi dello stomaco e della mammella: un antico antiossidante ?
1998
Sebastiano Venturi, Mattia Venturi e Marta Venturi
LINK
Does iodide in the gastric mucosa have an ancient antioxidant role ?
1998
Sebastiano Venturi and Marta Venturi
LINK Does dietary iodine prevent gastric cancer ?
1998
Venturi S, Stanghellini V, Donati FM, De Giorgio R, Barbara G, Salvioli B, Corinaldesi R.
LINK
Lo ioduro: un antico antiossidante
1999
Sebastiano Venturi and Marta Venturi
LINK

Iodide, thyroid and stomach carcinogenesis:
evolutionary story of a primitive antioxidant?
1999
Sebastiano Venturi and Marta Venturi
LINK

Role of iodine in evolution and carcinogenesis of
thyroid, breast and stomach
2000
S.Venturi, F.M. Donati, M.Venturi, A.Venturi, *L.Grossi and A. Guidi
LINK

Sequence of 123-iodide total-body scintiscans of a woman after intravenous injection of 123-iodide (half-life: 13 hours); (from left) respectively at 30 minutes, and at 6, 20 and 48 hours. High and rapid concentration of radio-iodide (in white) in extra-thyroidal organs is evident in gastric mucosa of the stomach, epidermis, salivary glands, periencephalic liquor, choroid plexus and oral mucosa. In gastric mucosa 131-iodide (half-life: 8 days) persists in scintiscans for more than 72 hours. In the thyroid, iodide-concentration is more progressive, as in a reservoir [from 1% (after 30 minutes) to 5.8 % (after 48 hours) of the total injected dose]. High iodide-concentration by the mammary gland is evident only in pregnancy and lactation. High excretion of radio-iodide is observed in the urine.

Environmental iodine deficiency:
a challenge to the evolution of terrestrial life ?
Sebastiano Venturi, Francesco M. Donati, Alessandro Venturi and Mattia Venturi
2000
LINK

Selenium and iodide: ancient antioxidants of cellular membrane lipids?
2000
Massimo Cocchi and Sebastiano Venturi.
LINK

Iodide, antioxidant function and omega-6 and omega-3 fatty acids.**
Progress in Nutrition. 2000;2, 1:15-19
Cocchi M and Venturi S.
LINK

Is there a role for iodine in breast diseases?
2001
Sebastiano Venturi
LINK

Iodine, helicobacter pylori, stomach cancer and evolution
2003
Venturi S, Grossi L, Marra GA, Venturi A, Venturi M
European Epi-Marker, 2003 Vol.7, 2 :1-7

Iodio ed Evoluzione ( Iodine and Evolution )
2004
Sebastiano Venturi § , Loris Grossi*, Gian Angelo Marra , Mattia Venturi e Alessandro Venturi
LINK

Iodine in Evolution of Salivary Glands and in Oral Health
2005
Sebastiano Venturi , Mattia Venturi
LINK

Iodio ed evoluzione
2006
Venturi Sebastiano, Venturi Mattia
LINK

Evolution of Dietary Antioxidants: Role of Iodine
2007
Venturi Sebastiano, Venturi Mattia
LINK

Evolution of Dietary Antioxidant Defences
2007
Venturi Sebastiano, Venturi Mattia
European Epi-Marker, 2007 Vol.11, 3 :1-12

Iodine, Stomach Cancer and Evolution
Beijng, Oct, 18-20, 2007
Venturi S, Venturi M.
LINK (5MB)

Vitamin C in Evolution
2007
Venturi S
LINK

Selenium: Evolution in Biology
2008
Venturi S.
LINK

Seminary: "Rola jodu pozatarczycowego w organizmie czlowieka"
POLISH ACADEMY of SCIENCES, PAN: Seminary in Nuclear Medicine and Biology, Krakow, Poland
February 29, 2008
Venturi S. and Venturi M.
LINK
Iodine, Thymus and Immunity
2009
Venturi S. and Venturi M.**
Nutrition, 2009; 25 (9) : 977-9
LINK Iodine in Evolution of Salivary Glands and in Oral Health
2009
Venturi S. and Venturi M.
Nutrition and Health. 2009; 20 (2) :119-134. PMID: 19835108
LINK
"Rola jodu pozatarczycowego w organizmie czlowieka"
POLISH ACADEMY of SCIENCES:
Seminary in Nuclear Medicine and Biology, Krakow, Poland
(Evolution of Dietary Antioxidant Defences)
May 15, 2010
Venturi S. and Venturi M.
LINK Thyroid Hormone, Iodine and Human Brain Evolution
2010
Venturi S. and Bégin M. E.
Chapter of book: "Environmental Influences on Human Brain Evolution"
by: Cunnane S. and Stewart K. Publisher: John Wiley, 2010. ISBN: 9780470452684
LINK

Evolution of Dietary Antioxidants
March 10-11, 2011, Hong Kong
5th International Functional Food Symposium
Venturi Sebastiano, Venturi Mattia
published in "PROGRESS IN NUTRITION", 2011, 13, 3 :226-227
and
   EVOLUTION of TERRESTRIAL ANTIOXIDANTS
Venturi Sebastiano, Venturi Mattia
Poster
LINK

Evolutionary significance of iodine
Sebastiano Venturi
Chapter of book published in Current Chemical Biology: Volume 5, 3 Issues, 2011
LINK
LINK

Sebastiano Venturi: quaranta anni di ricerche dei disturbi da carenza di iodio
e delle patologie tiroidee ed extratiroidee correlate
( Sebastiano Venturi: forty years of research on Iodine Deficiency Disorders and thyroidal and extrathyroidal pathologies )
Sebastiano Venturi 20 Agosto, 2012
LINK
La carenza di iodio nella provincia di Arezzo e in Toscana: ricerche di patologie tiroidee ed extratiroidee associate
Da "Il CESALPINO": Rivista dell'Ordine dei Medici di Arezzo. n. 32. Dicembre 2012 LINK

Sebastiano Venturi: quaranta anni di caccia ai segreti dello iodio.
Da "Il Notiziario": Rivista dell'Ordine dei Medici di Rimini. Dicembre 2012 LINK

La carenza iodica in Romagna Corso di aggiornamento per  MMG della AUSL di Rimini.
Google Gmail Audio Player

(Audio Player)
16 Feb. 2013 LINK
Iodine, Iodolipids, Antioxidants, Cancer & Evolution
2013
Sebastiano Venturi
LINK

Iodine, PUFAs and Iodolipids in Health and Diseases: an evolutionary perspective Human Evolution: Past, Present & Future: Anthropological, Medical & Nutritional Considerations. London, 8-10th May 2013 2013 Poster
Sebastiano Venturi

Iodine, PUFAs and Iodolipids in Health and Diseases: an evolutionary perspective.   Human Evolution: Past, Present & Future: Anthropological, Medical & Nutritional Considerations. London, 8-10th May 2013 S Venturi, CA Castellano, SC Cunnane 2013 Poster

Iodine, PUFAs and Iodolipids in Health and Diseases: An Evolutionary Perspective
In: "HUMAN EVOLUTION" vol. 29 (1-3), pagg. 185-205; 2014, Part 2 S. Venturi, M. Venturi, 2014 .........LINK.....

Iodine Deficiency in the Population of Montefeltro, A Territory in Central Italy
Inside the Regions of Emilia-Romagna, Tuscany and Marche

In: "INTERNATIONAL J. of ANTHROPOLOGY" , 29- n 1-2 (1-12) - 2014
Sebastiano Venturi, 2014
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Articles in Wikipedia Atherosclerosis
Wikipedia Molecular Evolution
Wikipedia Evolution of Terrestrial Antioxidants
Evolution_of_terrestrial_antioxidants Cancer
Wikipedia Antioxidants
Wikipedia Iodine
Wikipedia

Iodio
it.wikipedia.

IODINE in EVOLUTION. (2002)
Over three billion years ago, blue-green algae were the first living Prokaryota to produce oxygen in the atmosphere. About 700 million years ago (m/y/a) thyroxine (T4) is present in fibrous exoskeletal scleroproteins of the lowest invertebrates (sponges and corals) without showing any hormonal action. About 500-400 m/y/a some primitive marine fishes started to emerge from the iodine-rich sea (60 ug/L) and transferred to iodine-deficient fresh water (5-0.2 ug/L) and about 400-300 m/y/a these vertebrates evolved in amphibians and reptiles and transferred to I-deficient land. Therefore these vertebrates needed a new follicular organ: the thyroid gland, as reservoir of iodine. These vertebrates started to use its primitive T4 as transporter, into the peripherical cells, of antioxidant iodide and T3. The remaining T3 became the active hormone in the metamorphosis and thermogenesis for a better adaptation to terrestrial environment: fresh water, atmosphere, gravity, temperature and diet.